January 8, 2025
A Level Biology Revision (Year 13)

A Level Biology Revision (Year 13) “Chromatin and Histones”

Author: Freesciencelessons via YouTube
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A Level Biology Revision (Year 13)

In this video, we look at the role of chromatin and histones in gene expression. First we look at what is meant by heterochromatin and euchromatin. We then explore how histone acetylation and deacetylation can influence whether genes are expressed or whether they are silenced, including the roles of RNA polymerase and transcription factors.

Image credits:

DNA
https://commons.wikimedia.org/wiki/File:DNA_2_–_Smart-Servier.png
Laboratoires Servier, CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

Chromatin and histones
https://commons.wikimedia.org/wiki/File:Chromatin_and_histones.jpg
Darryl Leja, NHGRI, Public domain, via Wikimedia Commons

Cell nucleus
https://commons.wikimedia.org/wiki/File:Micrograph_of_a_cell_nucleus.png

Mitosis
https://commons.wikimedia.org/wiki/File:Mitosis_(261_10)_Pressed;_root_meristem_of_Vicia_faba_(cells_in_anaphase,_prophase).jpg
Doc. RNDr. Josef Reischig, CSc., CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

Human karyotype
https://commons.wikimedia.org/wiki/File:Human_male_karyotpe_high_resolution.jpg
Courtesy: National Human Genome Research Institute, Public domain, via Wikimedia Commons

Insulin
https://commons.wikimedia.org/wiki/File:Insulin_struct.png
User:AtikaAtikawa, CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

Antibody
https://commons.wikimedia.org/wiki/File:Antibody_IgG1_surface.png
Tokenzero, CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

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